Title of article
Synthesis and in vitro and in vivo evaluation of the 2-(6′methoxy-3′,4′-dihydro-1′-naphtyl)-4H-3,1-benzoxazin-4-one as a new potent substrate inhibitor of human leukocyte elastase
Author/Authors
Antonio Arcadi، نويسنده , , Cinzia Asti، نويسنده , , Laura Brandolini، نويسنده , , Gianfranco Caselli، نويسنده , , Fabio Marinelli، نويسنده , , Viviana Ruggieri، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
1291
To page
1294
Abstract
the title 2-vinyl-4H-3,1-benzoxazin-4-one has been synthesised and tested for inhibitory activity against human leukocyte elastase. The compound has shown activity both in vitro towards human sputum elastase and in vivo in an hemorrhagic assay.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790137
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