• Title of article

    Low-molecular-weight anti-HIV-1 peptides from the amino-terminal sequence of RANTES: possible lead compounds for coreceptor-directed anti-HIV-1 agents

  • Author/Authors

    Yasuhiro Nishiyama، نويسنده , , Tsutomu Murakami، نويسنده , , Keisuke Kurita، نويسنده , , Naoki Yamamoto، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    4
  • From page
    1357
  • To page
    1360
  • Abstract
    A series of small peptides corresponding to the amino-terminal sequence of RANTES were synthesized, and their anti-HIV-1 activity was evaluated. Pentapeptides, H-(10Ala-RANTES 6-10)-OH and Ac-(10Ala-RANTES 6-10)-NH2, were the smallest anti-HIV-1 peptides so far developed, and would be potentially important lead compounds for coreceptor-directed anti-HIV-1 drugs.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1999
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790149