Title of article
Synthesis and protein kinase C binding activity of benzolactam-V7
Author/Authors
Dawei Ma، نويسنده , , Guoqiang Wang، نويسنده , , Shaomeng Wang، نويسنده , , Alan P. Kozikowski، نويسنده , , Nancy E. Lewin، نويسنده , , Peter M. Blumberg، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
1371
To page
1374
Abstract
Benzolactam-V7 (3a), a simplified analogues of (−)-indolactam-V with twist-form conformation, was synthesized and evaluated as a new protein kinase C modulator. Both 3a and its-7-substituted analogue 3c showed weak binding activity to displace PDBU binding from recombinant PKCα.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790152
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