Title of article
Photoinduced cross-linking of RNA by cis-Rh(phen)2Cl2+ and cis-Rh(phen)(phi)Cl2+: A new family of light activatable nucleic acid cross-linking agents
Author/Authors
Noor-Ul-Iman and Taj Mohammad Khan، نويسنده , , Chaoping Chen، نويسنده , , Peixuan Guo، نويسنده , , Harry Morrison، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
1703
To page
1708
Abstract
The metal complexes, cis-Rh(phen)2Cl2+ and its more hydrophobic analog cis-Rh(phen)(phi)Cl2+, have been shown to photocross-link the 120-base 29-encoded pRNA. Primer extension on the cis-Rh(phen)(phi)Cl2+-photocross-linked RNA revealed that guanines are responsible for the interstrand cross-links.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790217
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