Title of article
Structure-activity relationship analysis of substituted 4-quinolinamines, antagonists of immunostimulatory CpG-oligodeoxynucleotides
Author/Authors
Lucjan Strekowski، نويسنده , , Oliwia Zegrocka، نويسنده , , Maged Henary، نويسنده , , Martial Say، نويسنده , , Maria J. Mokrosz، نويسنده , , Barbara M. Kotecka، نويسنده , , Lori Manzel، نويسنده , , Donald E. Macfarlane، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
1819
To page
1824
Abstract
On the basis of a systematic SAR analysis of substituted quinolines, a derivative 32 was synthesized that shows half-maximal inhibition of the immunostimulatory effect of CpG-oligodeoxynucleotides in vitro at the concentration of 0.24 nM.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790238
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