Title of article
Synthesis of water-soluble phenytoin prodrugs
Author/Authors
Joan Bosch، نويسنده , , Tomàs Roca، نويسنده , , Josep Domènech، نويسنده , , Montserrat Suriol، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
1859
To page
1862
Abstract
The synthesis of novel water-soluble phenytoin derivatives, bearing an ionizable group, and a preliminary study for in vitro blood hydrolysis are reported. The results show that hydrolysis of amino esters 8 is very fast, much more than that of fosphenytoin.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790245
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