Title of article
New class of biphenylene dibenzazocinones as potent ligands for the human EP1 prostanoid receptor
Author/Authors
Rejean Ruel، نويسنده , , Patrick Lacombe، نويسنده , , Mark Abramovitz، نويسنده , , Claude Godbout، نويسنده , , Sonia Lamontagne، نويسنده , , Chantal Rochette، نويسنده , , Nicole Sawyer، نويسنده , , Rino Stocco، نويسنده , , Nathalie M. Tremblay، نويسنده , , Kathleen M. Metters، نويسنده , , Marc Labelle، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
2699
To page
2704
Abstract
A new class of potent and selective ligands for the human EP1 prostanoid receptor is described. SAR studies reported herein allowed the identification of several potent dibenzazocinones bearing an acylsulfonamide side chain. The binding affinity of these compounds on all eight human prostanoid receptors is reported.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790409
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