Title of article
3-Acyloxy-2-phenalkylpropyl amides and esters of homovanillic acid as novel vanilloid receptor agonists
Author/Authors
Jeewoo Lee، نويسنده , , Shin-Ung Park، نويسنده , , JIYOUNG KIM ، نويسنده , , Jin-Kwan Kim، نويسنده , , Jiyoun Lee، نويسنده , , Uhtaek Oh، نويسنده , , Victor E. Marquez، نويسنده , , Maryam Beheshti، نويسنده , , Qiming J. Wang، نويسنده , , Shayan Modarres، نويسنده , , Peter M. Blumberg، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
2909
To page
2914
Abstract
A series of 3-acyloxy-2-phenalkylpropyl amides and esters of homovanillic acid were designed and synthesized as vanilloid receptor agonists containing the three principal pharmacophores of resiniferatoxin. Amide analogues 23, 5 and 11 were found to be potent agonists in vanilloid receptor assay both for ligand binding and for activation.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790451
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