Title of article
Inhibition ofE. coli growth by fullerene derivatives and inhibition mechanism
Author/Authors
Tadahiko Mashino، نويسنده , , Kensuke Okuda، نويسنده , , Takashi Hirota، نويسنده , , Masaaki Hirobe، نويسنده , , Tetsuo Nagano، نويسنده , , Masataka Mochizuki، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
2959
To page
2962
Abstract
Cationic ammonium fullerene derivatives (C60-bis(N,N-dimethylpyrrolidinium iodide) and C60-bis(N-methylpiperazinium iodide)) suppressedE. coli growth, whereas an anionic derivative (C60-dimalonic acid) did not. Both cationic derivatives inhibitedE. coli dioxygen consumption. Inhibition of energy metabolism is concluded to be a mechanism of the growth inhibition effect of fullerene derivatives.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790460
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