Title of article
Synthesis and apoptogenic activity of fluorinated ceramide and dihydroceramide analogues
Author/Authors
Steven De Jonghe، نويسنده , , Ilse Van Overmeire، نويسنده , , Johan Gunst، نويسنده , , André De Bruyn، نويسنده , , Chris Hendrix، نويسنده , , Serge Van Calenbergh، نويسنده , , Roger Busson، نويسنده , , Denis De Keukeleire، نويسنده , , Jan Philippé، نويسنده , , Piet Herdewijn، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
3159
To page
3164
Abstract
Short-chain 3-fluoro-(dihydro)ceramide analogues are synthesized from L-serine using diethylaminosulfur trifluoride (DAST) as fluorinating agent. The apoptogenic activity of these compounds was measured in three different cell lines and compared with their hydroxylated counterparts.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790499
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