Revised structure of a homonojirimycin isomer from Aglaonema treubii: First example of a naturally occurring α-homoallonojirimycin

The structure of a homonojirimycin isomer isolated from Aglaonema treublii and originally proposed as α-3,4-di-epi-homonojirimycin was revised to α-4-epi-homonojirimycin 3 (“α-homoallonojirimycin”) on the basis of NMR analysis and synthetic studies. Its activity as a glycosidase inhibitor is compared to that of other homonojirimycin isomers.