Title of article
Tokaramide A,a new cathepsin B inhibitor from the marine sponge Theonella aff. Mirabilis
Author/Authors
Nobuhiro Fusetani، نويسنده , , Masaki Fujita، نويسنده , , Yoichi Nakao، نويسنده , , Shigeki Matsunaga، نويسنده , , Rob W. M. van Soest، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
3397
To page
3402
Abstract
A new cathepsin B inhibitor, tokaramide A (1) has been isolated from the marine sponge Theonella aff. mirabilis. Its structure was determined by spectroscopic and chemical methods. Tokaramide A inhibits cathepsin B with an IC50 value of 29.0 ng/mL.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790543
Link To Document