• Title of article

    Delta opioid binding selectivity of 3-ether analogs of naltrindole

  • Author/Authors

    Andrew Coop، نويسنده , , Julia Pinto، نويسنده , , Lijuan Wang، نويسنده , , Karen McCullough، نويسنده , , Richard B. Rothman، نويسنده , , Christine Dersch، نويسنده , , Arthur E. Jacobson، نويسنده , , Kenner C. Rice، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    4
  • From page
    3435
  • To page
    3438
  • Abstract
    Masking of the 3-phenol of naltrindole as a range of ethers caused a decrease in binding affinity at all three opiate receptors (μ, κ, δ), however for the methyl ether, the reduction in affinity at both μ and κ was greater than at δ, thereby increasing δ binding selectivity.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1999
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790550