Title of article
A short synthesis of troglitazone: An antidiabetic drug for treating insulin resistance
Author/Authors
Janine Cossy، نويسنده , , Cecilia Menciu، نويسنده , , Haja Rakotoarisoa، نويسنده , , Philippe H. Kahn، نويسنده , , Jean-Roger Desmurs، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
2
From page
3439
To page
3440
Abstract
Troglitazone was obtained in 5 steps from 4-bromo-1,1-dimethoxy-3-methylbut-2-ene with an overall yield of 7.5%. The formation of the chromane ring was achieved by condensing an unsaturated acetal with trimethylhydroquinone in the presence of bis(trifluoromethylsulfonyl)imide.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790551
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