• Title of article

    The design, synthesis and activity of non-ATP competitive inhibitors of pp60c-src tyrosine kinase. Part 2: Hydroxyindole derivatives

  • Author/Authors

    Karen L. Milkiewicz، نويسنده , , Thomas H. Marsilje، نويسنده , , Richard P. WoodworthJr.، نويسنده , , Neil BifulcoJr.، نويسنده , , Matthew J. Hangauer، نويسنده , , David G. Hangauer، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    483
  • To page
    486
  • Abstract
    As part of a continuing effort to identify novel scaffolds that inhibit the pp60c-src protein tyrosine kinase, a series of hydroxyindole amides was rationally designed and synthesized. The most potent derivative was found to bind non-competitively with respect to ATP.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790669

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=790669