Title of article
Novel peptidomimetic hematoregulatory compounds
Author/Authors
Dirk A. Heerding، نويسنده , , Melanie Abruzzese، نويسنده , , Doreen Alberts، نويسنده , , Joelle Burgess، نويسنده , , James F. Callahan، نويسنده , , William F. Huffman، نويسنده , , Andrew G. King، نويسنده , , Stephen LoCastro، نويسنده , , Peter DeMarsh، نويسنده , , Louis M. Pelus، نويسنده , , Joanne S. Takata، نويسنده , , Pradip K. Bhatnagar، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
531
To page
534
Abstract
The activity of a novel series of peptidomimetic hematoregulatory compounds, designed based on a pharmacophore model inferred from the structure–activity relationships of a peptide SK&F 107647 (1), is reported. These compounds induce a hematopoietic synergistic factor (HSF) which in turn modulates host defense. The compounds may represent novel therapeutic agents in the area of hematoregulation.
Figure 1. Structure of SK&F 107647 (1).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790680
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