• Title of article

    The abasic site as a target for generation of locally multiply damaged sites

  • Author/Authors

    Alain Martelli، نويسنده , , Nathalie Berthet، نويسنده , , Jean-François Constant، نويسنده , , Martine Demeunynck، نويسنده , , Jean Lhomme، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    763
  • To page
    766
  • Abstract
    Abasic sites in DNA have been specifically targeted by synthetic compounds able to cleave DNA at abasic sites and to induce photodamages in the vicinity of the lesion. The synthesis and the photoactivity of the drugs on abasic sites containing DNA and oligonucleotides are reported.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790731