• Title of article

    The synthesis and evaluation of 2-substituted-7-(alkylidene)cephalosporin sulfones as β-lactamase inhibitors

  • Author/Authors

    John D. Buynak، نويسنده , , Venkata Ramana Doppalapudi، نويسنده , , A. Srinivasa Rao، نويسنده , , Sirishkumar D. Nidamarthy، نويسنده , , Greg Adam، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    5
  • From page
    847
  • To page
    851
  • Abstract
    A series of 2-substituted-7-(alkylidene)cephalosporin sulfones were prepared and evaluated as β-lactamase inhibitors. Compound 11c showed excellent activity as an inhibitor of the class C β-lactamase derived from Enterobacter cloacae, strain P99.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790750