• Title of article

    New fluorogenic substrate for the first continuous steroid sulfatase assay

  • Author/Authors

    Melitta Bilban، نويسنده , , Andreas Billich، نويسنده , , Manfred Auer، نويسنده , , Peter Nussbaumer، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    3
  • From page
    967
  • To page
    969
  • Abstract
    The screening for new inhibitors of steroid sulfatase requires an efficient test system. To overcome the shortcomings of the available discontinuous fluorimetric assay, several coumarin-type compounds were investigated as potential new substrates. 3,4-Benzocoumarin 7-O-sulfate was found to have appropriate substrate properties for the establishment of the first direct continuous assay of steroid sulfatase.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790775