• Title of article

    Cyclic thioether peptide mimetics as VCAM–VLA-4 antagonists

  • Author/Authors

    Nader Fotouhi، نويسنده , , Pramod Joshi، نويسنده , , Jefferson W. Tilley، نويسنده , , Karen Rowan، نويسنده , , Virginia Schwinge، نويسنده , , Barry Wolitzky، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    3
  • From page
    1167
  • To page
    1169
  • Abstract
    Selective substitution of a sulfur atom by carbon in a highly potent 13-membered cyclic disulfide was accomplished by intramolecular displacement of a bromide. The potency of the resulting thioethers in the VCAM/VLA-4 assay was dependant on ring size and the position of the sulfur atom.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790825