Title of article
Conformationally-restricted ligands for the histamine H1 receptor
Author/Authors
Christopher Upton، نويسنده , , Richard H. Osborne، نويسنده , , Mohammad Jaffar، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
3
From page
1277
To page
1279
Abstract
Potent H1-antagonistic activity in a series of novel indeno[2,1-c]pyridines and their 4-arylpiperidinol precursors is reported; one compound shows an in vitro activity four times that of the standard mepyramine that it was screened against. Their failure to translate this protection to in vivo tests is discussed.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790851
Link To Document