Title of article
sp2-bridged diaryl retinoids: Effects of bridge-region substitution on retinoid x receptor (RXR) selectivity
Author/Authors
Marcia I. Dawson، نويسنده , , Peter D. Hobbs، نويسنده , , Ling Jong، نويسنده , , Dongmei Xiao، نويسنده , , Wan-ru Chao، نويسنده , , Chin Pan، نويسنده , , Xiaokun Zhang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
1307
To page
1310
Abstract
RXR class selectivity and RXR transcriptional activation activity compared to those for the retinoic acid receptor subtypes were enhanced on the 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenylethenyl)benzoic acid scaffold and its 3-methyl analogue by replacing their 1,1-ethenyl bridge by a 1,1-(2-methylpropenyl) or cyclopropylidenylmethylene group.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790859
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