Title of article
Convergent synthesis of ribonuclease L-active 2′,5′-oligoadenylate-peptide nucleic acids
Author/Authors
Zhengfu Wang، نويسنده , , Ling Chen، نويسنده , , Suzanne F. Bayly، نويسنده , , Paul F. Torrence، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
1357
To page
1360
Abstract
2-5A was conjugated to N-(2-aminoethyl)-glycyl PNA by periodate oxidization, followed by coupling with amino-derivatized PNA and final cyanoborohydride reduction. An adduct of 2-5A pentamer with tetrameric thymine PNA activated RNase with the same potency as earlier versions of 2-5A-PNA or 2-5A-DNA.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790870
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