Title of article
Synthesis and in vitro evaluation of human FP-receptor selective prostaglandin analogues
Author/Authors
Mitchell A. deLong، نويسنده , , Jack Amburgey، نويسنده , , Cynthia Taylor، نويسنده , , John A. Wos، نويسنده , , David L. Soper، نويسنده , , Yili Wang، نويسنده , , Renee Hicks، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
1519
To page
1522
Abstract
The in vitro evaluation of a series of saturated prostaglandins revealed that compounds with omega chain aromatic rings retain nanomolar potency for the human prostaglandin F receptor (hFP receptor), exemplified by compound 8. In contrast, the double bonds are required for activity in the series with an acyclic omega chain as in PGF2α.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790911
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