Title of article
Kinetic characterisation of ene-diol-based inhibitors of α-amylase
Author/Authors
Juliet A. Gerrard، نويسنده , , Maureen J. Prince، نويسنده , , Andrew D. Abell، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
2
From page
1575
To page
1576
Abstract
A kinetic analysis of the inhibition of malt α-amylase by compounds based on ascorbic acid has shown the mode of inhibition to be competitive for the parent compound, but more complex for its derivatives. We have further simplified the ascorbic acid ene-diol pharmacophore by demonstrating that dihydroxyfumaric acid is also a good inhibitor of malt α-amylase.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790924
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