Title of article
DNA Triple Helix Stabilization by Aminoglycoside Antibiotics
Author/Authors
Dev P. Arya، نويسنده , , R. Lane CoffeeJr.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
3
From page
1897
To page
1899
Abstract
The stabilization of the poly(dA)√2poly(dT) triple helix by neomycin is reported. Preliminary results indicate that neomycin stabilizes DNA triple helices and the double helical structures composed of poly(dA)√poly(dT) are virtually unaffected. This is the first report of the interaction of aminoglycoside antibiotics with DNA triple helices.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791001
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