• Title of article

    5-HETE congeners as modulators of cell proliferation

  • Author/Authors

    Thomas A. Miller، نويسنده , , Jagadananda Ghosh، نويسنده , , Charles E. Myers، نويسنده , , Timothy L. Macdonald، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    1913
  • To page
    1916
  • Abstract
    The synthesis and assessment of the mitogenic properties of 5-HETE congeners are reported. These studies represent an effort to develop a structure–activity profile for ligands of the 5-HETE/5-oxoETE G-protein coupled receptor(s). Many of these agents possess mitogenic activity that equals or exceeds that of racemic 5-HETE family constituents in prostate cancer cell lines.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    791005