Title of article
Enhanced Pneumocystis carinii activity of new primaquine analogues
Author/Authors
Thomas E. Goodwin، نويسنده , , Carole J. Boylan، نويسنده , , William L. Current، نويسنده , , John C. Byrd، نويسنده , , Clint B. Edwards، نويسنده , , Danny A. Fuller، نويسنده , , Jennifer L. Green، نويسنده , , Christine D. Larocca، نويسنده , , Kevin D. Raney، نويسنده , , Ashley S. Ross، نويسنده , , W. Andrew Tucker، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
2205
To page
2208
Abstract
New analogues of the venerable antimalarial drug primaquine have been synthesized and bioassayed in vivo against Pneumocystis carinii, a life-threatening infection common among immunosuppressed patients. Two of these new compounds are significantly more active than primaquine itself, and provide new information for future drug design and development in this area.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791073
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