Title of article
Synthesis and antiproliferative evaluation of 7-aminosubstituted pyrroloiminoquinone derivatives
Author/Authors
Valérie Bénéteau، نويسنده , , Alain Pierré، نويسنده , , Bruno Pfeiffer، نويسنده , , Pierre Renard، نويسنده , , Thierry Besson، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
2231
To page
2234
Abstract
Coupling of five amines on the 7-methoxy-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline core was achieved and afforded, in particular, an opened analogue of the natural alkaloid wakayin. Evaluation of cytotoxic activity of compounds 2, 10–13 on L1210 cells afforded IC50 in the range 0.25–5.3 μM.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791078
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