Title of article
7-Alkyl- and 7-Cycloalkyl-5-aryl-pyrrolo[2,3-d]pyrimidines—potent inhibitors of the tyrosine kinase c-Src
Author/Authors
Leo Widler، نويسنده , , Jonathan Green، نويسنده , , Martin Missbach، نويسنده , , Mira u a، نويسنده , , Eva Altmann، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
849
To page
852
Abstract
7-Substituted-5-aryl-pyrrolo[2,3-d]pyrimidines have been prepared starting from α-bromoacetophenones. These compounds represent a novel class of potent inhibitors of the tyrosine kinase pp60c-Src with good specificity towards other tyrosine kinases (EGF-R, v-Abl).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791290
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