Title of article
Synthesis of potent and selective dopamine D4 antagonists as candidate radioligands
Author/Authors
Yiyun Huang، نويسنده , , Lawrence S. Kegeles، نويسنده , , Sung-A Bae، نويسنده , , Dah-Ren Hwang، نويسنده , , Bryan L. Roth، نويسنده , , Jason E. Savage، نويسنده , , Marc Laruelle، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
3
From page
1375
To page
1377
Abstract
A series of dopamine D4 antagonists was synthesized and evaluated as potential candidates for development as positron emission tomography (PET) radioligands. All new compounds display high affinity and selectivity for the D4 receptors and compounds 5b, 5d, and 5e were identified as candidates for radioligand development.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791413
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