Title of article
Dibasic Inhibitors of Human Mast Cell Tryptase. Part 3: Identification of a Series of Potent and Selective Inhibitors Containing the Benzamidine Functionality
Author/Authors
Jeffrey M. Dener، نويسنده , , Kenneth D. Rice، نويسنده , , William S. Newcomb، نويسنده , , Vivian R. Wang، نويسنده , , Wendy B. Young، نويسنده , , Anthony R. Gangloff، نويسنده , , Elaine Y. -L. Kuo، نويسنده , , Lynne Cregar، نويسنده , , Daun Putnam، نويسنده , , Martin Wong، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
5
From page
1629
To page
1633
Abstract
A survey of charged groups and linkers for a series of symmetrical and unsymmetrical dibasic inhibitors is described, leading to several classes of potent and selective inhibitors. In particular, the benzamidine functionality was identified as the most potent charged group investigated.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791467
Link To Document