Title of article
Synthesis and biological evaluation of novel bisindolylmaleimides that inhibit vascular endothelial cell proliferation
Author/Authors
Miguel F. Bra?a، نويسنده , , Loreto A?orbe، نويسنده , , Gema Tarras?n، نويسنده , , Francesc Mitjans، نويسنده , , Jaume Piulats، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
3
From page
2701
To page
2703
Abstract
A novel class of bisindolylmaleimides were synthesized and antiproliferative activities (HUVECs and three tumor cell lines) of these compounds were investigated. Two water-soluble derivatives, 10 and 12, possessing a dimethylaminoalkoxy side chain in their structure, showed interesting activity and selectivity on HUVECs proliferation.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791711
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