Title of article
Visualizing antibody-Catalyzed retro-Aldol-Retro-Michael reactions
Author/Authors
Fujie Tanaka، نويسنده , , Lisa Kerwin، نويسنده , , Diane Kubitz، نويسنده , , Richard A. Lerner، نويسنده , , Carlos F. Barbas III، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
2983
To page
2986
Abstract
We developed a visible detection system for antibody-catalyzed retro-aldol-retro-Michael reactions. Aldolase antibody 38C2 catalyzed the reaction of substrate 1 to provide 6-bromo-2-napthol that forms a visible colored azo dye with diazonium salts. This system has potential for the screening of novel catalysts.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791775
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