Title of article
New readily accessible peroxides with High Anti-malarial Potency
Author/Authors
Nobutoshi Murakami، نويسنده , , Motoyuki Kawanishi، نويسنده , , Sawako Itagaki، نويسنده , , Toshihiro Horii، نويسنده , , Motomasa Kobayashi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
69
To page
72
Abstract
In an explorative study for new anti-malarial substances using the methyl esters (1 and 2) of peroxyplakoric acids A3 and B3 as scaffolds, 6-carbomethoxymethyl-3-methoxy-3-pentyl-1,2-dioxane, which has been readily synthesized from 6-keto-α,β-unsaturated ester, was found to exhibit potent anti-malarial activity with high selective toxicity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791893
Link To Document