Title of article
Oxyaniliniums as acetylcholinesterase inhibitors for the reversal of neuromuscular block
Author/Authors
Simon J. A. Grove، نويسنده , , Jasmit Kaur، نويسنده , , Alan W. Muir، نويسنده , , Eleanor Pow، نويسنده , , Gary J. Tarver، نويسنده , , Mingqiang Zhang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
193
To page
196
Abstract
A series of oxyanilinium-based AChE inhibitors have been synthesised and tested for the reversal of vecuronium-induced neuromuscular block. Several compounds, for example 2-hydroxy- and 2-methoxy-N,N-dimethyl-N-allylanilinium bromide (3 and 6) showed comparable reversal potencies to edrophonium and clean in vivo cardiovascular profiles.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791933
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