• Title of article

    Cytotoxicity of 6,16-Disubstituted analogues of (−)-Vincadifformine

  • Author/Authors

    Guy Lewin، نويسنده , , Reynald Hocquemiller، نويسنده , , Corinne Schaeffer، نويسنده , , Pierre-Hervé Lambert، نويسنده , , Stephane Leonce، نويسنده , , Alain Pierré، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    371
  • To page
    374
  • Abstract
    Eight analogues of (−)-16-chloro-1-dehydro-6S-bromovincadifformine 1 were synthesized and evaluated for cytotoxicity in L1210 cell culture. None of the new compounds was more active than 1 but the modulation at C6, C16 and on the aromatic ring at C10 informs about structure–activity relationships within this series.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2002
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    791975

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=791975