Title of article
Peptidomimetics of Efflux Pump Inhibitors Potentiate the Activity of Levofloxacin in Pseudomonas aeruginosa
Author/Authors
Thomas E. Renau، نويسنده , , Roger Léger، نويسنده , , Rose Yen، نويسنده , , Miles W. She، نويسنده , , Eric M. Flamme، نويسنده , , Joan Sangalang، نويسنده , , Carla L. Gannon، نويسنده , , Suzanne Chamberland، نويسنده , , Olga Lomovskaya، نويسنده , , Ving J. Lee، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
763
To page
766
Abstract
Several classes of peptidomimetics of the efflux pump inhibitor -ornithine- -homophenylalanine-3-aminoquinoline (MC-02,595) have been prepared and evaluated for their ability to potentiate the activity of the fluoroquinolone levofloxacin in Pseudomonas aeruginosa. A number of the new analogues were as active or more active than the lead, demonstrating that a peptide backbone is not essential for activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792063
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