• Title of article

    Anthranilate sulfonamide hydroxamate TACE inhibitors. Part 1: Structure-based design of novel acetylenic P1′ groups

  • Author/Authors

    James M. Chen، نويسنده , , Guixian Jin، نويسنده , , Amy Sung، نويسنده , , Jeremy I. Levin، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    1195
  • To page
    1198
  • Abstract
    The structure-based design of potent sulfonamide hydroxamate TACE inhibitors bearing novel acetylenic P1′ groups has led to compounds with excellent in vitro potency against TACE and selectivity over MMP-1.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2002
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    792172

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=792172