Title of article
In vivo active antimalarial isonitriles
Author/Authors
Chandan Singh، نويسنده , , Naveen Chandra Srivastav، نويسنده , , Sunil K. Puri، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
3
From page
2277
To page
2279
Abstract
Building on the lead from antimalarial isonitriles 1–4 of marine origin, several easily accessible synthetic isonitriles were assessed for their antimalarial activity against Plasmodium falciparum (in vitro) and multidrug resistant Plasmodium yoelii in Swiss mice model (in vivo). Isonitrile 11 has shown promising activity in both these assays.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792423
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