Title of article
Novel Inhibitors of Plasminogen Activator Inhibitor-1: Development of New Templates From Diketopiperazines
Author/Authors
Shouming Wang، نويسنده , , Julian Golec، نويسنده , , Warren Miller، نويسنده , , Sandra Milutinovic، نويسنده , , Adrian Folkes، نويسنده , , Susannah Williams، نويسنده , , Teresa Brooks، نويسنده , , Kevin Hardman، نويسنده , , Peter Charlton، نويسنده , , Stephen Wren، نويسنده , , John Spencer، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
2367
To page
2370
Abstract
Several isoquinoline-based templates were identified from the studies of the conformational effects of the diketopiperazine structures for PAI-1 inhibition. Moderate to good activity was retained with the elimination of unattractive characteristics in the diketopiperazine template.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792449
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