• Title of article

    Quaternary Salts of E2020 Analogues as Acetylcholinesterase Inhibitors for the Reversal of Neuromuscular Block

  • Author/Authors

    John K. Clark، نويسنده , , Phill Cowley، نويسنده , , Alan W. Muir، نويسنده , , Ronald Palin، نويسنده , , Eleanor Pow، نويسنده , , Alan B. Prosser، نويسنده , , Robert Taylor، نويسنده , , Mingqiang Zhang، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    2565
  • To page
    2568
  • Abstract
    A series benzylpiperidinium and benzylpyridinium quaternary salts have been synthesised and tested for inhibition of acetylcholinesterase and reversal of neuromuscular block induced by vecuronium. Several potent reversal agents have been identified and their haemodynamic effects measured.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2002
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    792496