Title of article
8-Anilinoimidazo[4,5-g]quinoline-7-carbonitriles as Src Kinase Inhibito
Author/Authors
Dan Berger، نويسنده , , Minu Dutia، نويسنده , , Dennis Powell، نويسنده , , Biqi Wu، نويسنده , , Allan Wissner، نويسنده , , Frenel DeMorin، نويسنده , , Jennifer Weber، نويسنده , , Frank Boschelli، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
5
From page
2761
To page
2765
Abstract
A series of 8-anilinoimidazo[4,5-g]quinoline-7-carbonitriles was synthesized and evaluated as Src kinase inhibitors. Several aniline substituents were surveyed, as well as water-solubilizing groups at the C-2 and N-3 positions. Potent Src inhibitors were identified, with N-3 providing the best position for an additional water-solubilizing group.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792537
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