Title of article
Acyl dipeptides as reversible caspase inhibitors. Part 1: Initial Lead Optimization
Author/Authors
Steven D. Linton، نويسنده , , Donald S. Karanewsky، نويسنده , , Robert J. Ternansky، نويسنده , , Joe C. Wu، نويسنده , , Brian Pham، نويسنده , , Lalitha Kodandapani، نويسنده , , Robert Smidt، نويسنده , , Jose Luis Diaz-Rossello، نويسنده , , Lawrence C. Fritz، نويسنده , , Kevin J. Tomaselli، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
3
From page
2969
To page
2971
Abstract
Parallel synthesis was used to explore the SAR of a peptidomimetic caspase inhibitor. The most potent compound had nanomolar activity against caspases 1, 3, 6, 7, and 8.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792580
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