Title of article
DNA Interaction and photonicking properties of DNA-Targeted acridine (2,2′-Bipyridine)Platinum(II) complexes
Author/Authors
Lourdes Gude، نويسنده , , Mar?a-José Fern?ndez، نويسنده , , Kathryn B. Grant، نويسنده , , Antonio Lorente، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
5
From page
3135
To page
3139
Abstract
Synthesis of two (2,2′-bipyridine)platinum(II) complexes tethered to one or two acridine chromophores is reported. These acridine complexes efficiently unwind and photocleave supercoiled plasmid DNA under physiological conditions of temperature and pH.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792617
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