Title of article
5-Azidoepibatidine: an exceptionally potent photoaffinity ligand for neuronal α4β2 and α7 nicotinic acetylcholine receptors
Author/Authors
Nanjing Zhang، نويسنده , , Motohiro Tomizawa، نويسنده , , John E. Casida، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
3
From page
525
To page
527
Abstract
Racemic 5-azidoepibatidine [(±)-1] was synthesized via 5-aminoepibatidine as a candidate photoaffinity ligand with exceptionally high affinity at the mammalian neuronal nicotinic receptors (Ki values of 0.027 nM for α4β2 and 9.7 nM for α7) and excellent photoreactivity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792958
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