Title of article
Facile synthesis of [11C]edrophonium and its analogues as new potential PET imaging agents for heart acetylcholinesterase
Author/Authors
Qi-Huang Zheng، نويسنده , , Xuan Liu، نويسنده , , Xiangshu Fei، نويسنده , , Ji-Quan Wang، نويسنده , , Bruce H. Mock، نويسنده , , Barbara E. Glick-Wilson، نويسنده , , Michael L. Sullivan، نويسنده , , Gary D. Hutchins، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
1787
To page
1790
Abstract
[11C]Edrophonium and its analogues have been synthesized for evaluation as new potential positron emission tomography (PET) imaging agents for heart acetylcholinesterase. The tracers were prepared by N-[11C]methylation of precursors using [11C]methyl triflate and isolated by solid-phase extraction (SPE) purification procedure in 50–65% radiochemical yields.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793235
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