Title of article
Novel water soluble 2,6-dimethoxyphenyl ester derivatives with intravenous anaesthetic activity
Author/Authors
D. Jonathan Bennett، نويسنده , , Alison Anderson، نويسنده , , Kirsteen Buchanan، نويسنده , , Alan Byford، نويسنده , , Andrew Cooke، نويسنده , , David K. Gemmell، نويسنده , , Niall M. Hamilton، نويسنده , , Maurice S. Maidment، نويسنده , , Petula McPhail، نويسنده , , Donald F. M. Stevenson، نويسنده , , Hardy Sundaram، نويسنده , , Peter Vijn، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
5
From page
1971
To page
1975
Abstract
A number of water soluble bis-amino-2,6-dimethoxyphenyl ester derivatives were found to exhibit improved anaesthetic activity in mice relative to propofol 1. Of the analogues disclosed, 44 was further profiled in rodents and found to be a superior agent to propofol for the induction and maintenance of anaesthesia.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793277
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