• Title of article

    Dihydroquinolines with amine-containing side chains as potent n-NOS inhibitors

  • Author/Authors

    Stefan Jaroch، نويسنده , , Peter H?lscher، نويسنده , , Hartmut Rehwinkel، نويسنده , , Detlev Sülzle، نويسنده , , Gerardine Burton، نويسنده , , Margrit Hillmann، نويسنده , , Fiona M. McDonald، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2003
  • Pages
    4
  • From page
    1981
  • To page
    1984
  • Abstract
    Dihydroquinolines with aminoalkyl side chains have been synthesized and have been shown to be potent n-NOS inhibitors. A marked selectivity versus e-NOS of up to approximately 300-fold was observed, whereas i-NOS was moderately inhibited.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2003
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    793279