Title of article
Synthesis of radiolabeled biphenylsulfonamide matrix metalloproteinase inhibitors as new potential PET cancer imaging agents
Author/Authors
Xiangshu Fei، نويسنده , , Qi-Huang Zheng، نويسنده , , Xuan Liu، نويسنده , , Ji-Quan Wang، نويسنده , , Hui Bin Sun، نويسنده , , Bruce H. Mock، نويسنده , , K. Lee Stone، نويسنده , , Kathy D. Miller، نويسنده , , George W. Sledge Jr، نويسنده , , Gary D. Hutchins، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
6
From page
2217
To page
2222
Abstract
Novel matrix metalloproteinase (MMP) inhibitor radiotracers, (S)-3-methyl-2-(2′,3′,4′-methoxybiphenyl-4-sulfonylamino)-butyric acid [11C]methyl ester (1a–c), (S)-3-methyl-2-(2′,3′,4′-fluorobiphenyl-4-sulfonylamino)-butyric acid [11C]methyl ester (1d–f), and (S)-3-methyl-2-(4′-nitrobiphenyl-4-sulfonylamino)-butyric acid [11C]methyl ester (1g), a series of substituted biphenylsulfonamide derivatives, have been synthesized for evaluation as new potential positron emission tomography (PET) cancer imaging agents.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793329
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